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과체중 및 비만 환자의 체중감량을 위한 식사량 조절 및 복합 한약 단기 치료(5일 레스큐 프로그램)의 효과와 안전성: 진료기반 연구
Effect and Safety of Calorie Restriction and Complex Herbal Medicine Short-term Treatment (‘Oil-rescue’ Program) for Weight Reduction of Obesity or Overweight Patients: A Practice Based Research
J Korean Med Obes Res 2020;20:122-30
Published online December 31, 2020;  https://doi.org/10.15429/jkomor.2020.20.2.122
Copyright © 2020 The Society of Korean Medicine for Obesity Research.

권병조⋅이은지1,2†⋅장정현3⋅송창은4⋅이혜련5⋅김정은6⋅윤영희6⋅최예용6⋅윤상훈⋅임정태6,7
Byeongjo Kwon, Eunji Lee1,2†, Jeonghyun Chang3, Changeun Song4, Hyeryun Lee5, Jungeun Kim6, Younghee Yun6, Ye-yong Choi6, Sang-Hoon Yoon, Jungtae Leem6,7

청연한의원, 1청연중앙연구소, 2청연한방병원, 3365화사한의원, 4365헬리오한의원, 5원광대학교 대학원 한의학과, 6㈜CY 기업부설연구소, 7원광대학교 한국전통의학연구소

Chung-Yeon Korean Medicine Clinic, 1Chung-Yeon Central Institute, 2Chung-Yeon Korean Medicine Hospital, 3365 Hwasa Korean Medicine Clinic, 4365 Helio Korean Medicine Clinic, 5Department of Korean Medicine, Graduate School of Wonkwang University, 6Research and Development Institute, CY Pharma Co., 7Korea Bio Medical Science Institute, Wonkwang University
Sang-Hoon Yoon
Chung-Yeon Korean Medicine Clinic, 404 Nonhyeon-ro, Gangnam-gu, Seoul 06224, Korea
Tel: +82-2-565-6800
Fax: None
E-mail : chin9yaaaa@gmail.com

Jungtae Leem
Research and Development Institute, CY Pharma Co., 340 Nonhyeon-ro, Gangnam-gu, Seoul 06227, Korea
Tel: + 82-2-2039-7640
Fax: +82-2-2039-7639
E-mail: julcho@naver.com

These authors contributed equally to this work as co-first authors.
Received October 14, 2020; Revised November 21, 2020; Accepted December 4, 2020.
cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objectives: This study is a practice based research conducted to investigate the effectiveness and safety of a 5-day short-term diet program (‘Oil-rescue’ program) designed to reduce the adverse events and initial dropout rate in obesity treatment.
Methods: We retrospectively analyzed 4 Korean medicine clinic patient data who completed ‘Oil-rescue’ program which is consisting of Gambi-hwan, Bium-hwan, Butgiban-hwan and Jayoon Kyungokgo. The weight change before and after participating ‘Oil-rescue’ program was primary outcome of our study. Changes in body mass index, body fat mass, skeletal muscle mass, body water content, lean body mass, protein, and minerals were also measured.
Results: A total of 35 patients who satisfied the eligible criteria were finally included. The body weight decreased from 69.45±11.86 kg to 67.43±11.58 kg, a total of 2.02±1.03 kg (P<0.001). Body fat mass decreased from 25.77±7.45 kg to 24.98±7.26 kg, a total of 0.78±1.21 kg (P<0.001). Body mass index decreased from 26.39±3.64 kg/m2 to 25.64±3.49 kg/m2 , a total of 0.75±0.41 kg/m2 . (P<0.001). A total of 15 patients had side effects such as diarrhea, abdominal pain, and insomnia, but all were mild. 16 out of 35 people switched to long-term obesity treatment programs.
Conclusions: Through this retrospective practice based research, it was found that the ‘Oil-rescue’ program effectively reduced body weight, body fat, and body mass index, and the other obesity related parameters. It was a relatively safe and effective short-term obesity treatment program.
Keywords : Anti-obesity agents, Gambi-hwan, Korean traditional medicine, Adverse effects, Ephedrine


December 2020, 20 (2)
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