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고지방 식이를 섭취한 흰쥐에서 발효 삼정환의 항비만 효과
Anti-Obesity Effects of Fermented Samjung-hwan in Hign Fat Diet Rats
J Korean Med Obes Res 2013;13:17-23
Published online June 30, 2013
Copyright © 2013 The Society of Korean Medicine for Obesity Research.

송미영ㆍShambhunath Boseㆍ김호준
Miyoung Song, Shambhunath Bose, Hojun Kim

동국대학교 한의과대학 한방재활의학과교실

Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dongguk University
Hojun Kim
Department of Oriental Rehabilitation Medicine, Dongguk University Ilsan Oriental Hospital, College of Oriental Medicine, Dongguk University, 27 Dongguk-ro, Ilsandong-gu, Goyang 410-773, Korea
Tel: +82-31-961-9111
Fax: +82-31-961-9009
E-mail: kimklar@dongguk.ac.kr
Received May 28, 2013; Revised June 6, 2013; Accepted June 6, 2013.
Abstract
Objectives: This study was performed to evaluate the effects of fermented Samjung-hwan (SJH) extracts on weight, serum lipids and blood glucose.
Methods: SJH was fermented using three different probiotic bacterial strains (Lactobacillus plantarum [LP], Leuconostoc mesenteroides [LM], Bifidobacterium longum [BL]) separately. Thirty-six rats were divided into normal, control (high fat diet), SJH-UF (high fat diet+unfermented SJH 200 mg/kg), SJH-LP (high fat diet+LP fermented SJH 200 mg/kg), SJH-LM (high fat diet+LM fermented SJH 200 mg/kg) and SJH-BL (high fat diet+BL fermented SJH 200 mg/kg). For 8 weeks later, we examined body weight, total cholesterol, high-density lipoprotein (HDL)-cholesterol and blood glucose.
Results: The control group showed significantly increased weight gain compared with normal group and SJH-LP and BL groups had less weight gain than control group, significantly. In the lipid serum tests, control group showed significantly increased total cholesterol levels compared with normal group and only SJH-LP represented decreased total cholesterol levels compared with control group. However there was no significant change in the HDL-cholesteol levels. In the blood glucose tests, that of control group significantly incereased more than that of normal group, SJH-BL showed significantly decreased blood glucose levels compared with control group.
Conclusions: SJH-LP, SJH-BL showed weight control effect, SJH-LP decreased TC and SJH-BL reduced blood glucose.
Keywords : Samjung-hwan, Fermentation, Lactobacillus plantarum, Leuconostoc mesenteroides, Bifidobacterium longum, Obesity

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