Fig. 2. Effect of COME t reatment o n adipose tissue weight in high-fat diet-fed C57BL/6 mice. Mice fed with high-fat diet were t reated with COME or GCE b y oral g avage for 8 weeks. (A) Body fat mass percentage and (B) lean mass percentage were measured using dual-energy x-ray absorptiometry. (C) Adipose tissue weight in epididymal, retroperitoneal, mesenteric, and inguinal fat. (D) Total white adipose tissue weights were calculated as the sum of epididymal, retroperitoneal, mesenteric, and inguinal fat. Values are expressed as the mean±SEM (n=8). COME: Cydonia oblonga Miller fruit extract, GCE: Garcinia cambogia extract, CD: control diet, HFD: high-fat diet, H+C: HFD+400 mg/kg body weight/day Cydonia oblonga Miller fruit extract, H+G: HFD+400 mg/kg body weight/day Garcinia cambogia extract, WAT: white adipose tissue, SEM: standard error of the mean. Means without a common letter differ at P<0.05.
