Summary of Cell Experiment
| Author | Year | Subject | Injection | Metrics | Result |
|---|---|---|---|---|---|
| Lee12) | 2020 | 3T3-L1 | - Lipid accumulation - ATGL, HSL - LC3, ATG5, ATG7 |
- Lipid accumulation decreased - Level of ATGL, HSL, LC3, ATG5, ATG7 increased |
|
| Kang24) | 2014 | 3T3-L1 | - C/EBP β, C/EBP δ, C/EBPα, PPAR-γ - aP2, adipsin, LPL, CD36, TGF-β, leptin - LXRα, FAS - TNF-α, IL-1β, IL-6, IFN-γ, GM-CSF |
- Level of C/EBP β, C/EBP δ, C/EBPα, aP2, adipsin, LPL, CD36, TGF-β, Leptin, LXRα, FAS, TNF-α decreased - Fat synthesis suppressed - Adipocyte-induced pro-inflammatory cytokines were reduced |
|
| Kim et al21) | 2012 | 3T3-L1/Macrophage | WGC pharmacopuncture | - Cell viability - NO production - Shape of fat cells - Adiponectin, PPAR-γ, iNOS, COX-2, NF-κB |
1. 3T3-L1: Lipid accumulation decreased - NO production increased - Differentiation of fat cells suppressed 2. Macrophage: NO production reduced - Level of iNOS, COX-2, NF-κB decreased |
ATGL: adipose triglyceride lipase, HSL: hormone sensitive lipase, LC3: light chain 3, ATG: autophagy related, C/EBP: CCAAT enhancer binding protein, PPAR-γ: proliferator-activated receptor gamma, aP2: adipocyte fatty acid binding protein, LPL: lipoprotein lipase, CD36: cluster determinant 36, TGF-β: transforming growth factor-β, LXRα: the liver X receptor α, FAS: fatty acid synthase, TNF-α: tumor necrosis factor-α, IL: interleukin, IFN-γ: interferon gamma, GM-CSF: granulocyte-macrophage colony-stimulating factor, WGC: wild ginseng complex, NO: nitric oxide, iNOS: inducible nitric oxide synthase, COX-2: cyclooxygenase-2, NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cell.
