Outcome Changes at Week 4 and Week 12
| Variables | Baseline (week 0) | Week 4 | Week 4 - Baseline | P-value | Week 12 | Week 12 - Baseline | P-value | Week 4 - Baseline | Week 12 - Week 4 | Δ | P-value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Weight (kg) | 77.27 (72.61, 81.92) | 74.61 (70.02, 79.20) | -2.66 (-3.25, -2.06) | <.0001 |
74.30 (69.58, 79.01) | -2.97 (-3.82, -2.12) | <.0001 |
-2.66 (-3.25, -2.06) | -0.31 (-0.89, 0.27) | 2.34 (1.53, 3.16) | <.0001 |
| BMI (kg/m2) | 29.14 (28.06, 30.22) | 28.13 (27.02, 29.24) | -1.01 (-1.26, -0.77) | <.0001 |
27.96 (26.78, 29.13) | -1.18 (-1.50, -0.86) | <.0001 |
-1.01 (-1.26, -0.77) | -0.17 (-0.38, 0.04) | 0.84 (0.51, 1.17) | <.0001 |
| WC (cm) | 94.78 (91.24, 98.33) | 91.40 (87.65, 95.15) | -3.38 (-4.30, -2.47) | <.0001 |
90.07 (86.31, 93.83) | -4.71 (-6.06, -3.36) | <.0001 |
-3.38 (-4.30, -2.47) | -1.33 (-2.25, -0.41) | 2.05 (0.81, 3.29) | 0.0018 |
| HC (cm) | 104.9 (102.7, 107.1) | 101.7 (99.6, 103.8) | -3.20 (-4.08, -2.31) | <.0001 |
101.2 (99.1, 103.3) | -3.73 (-4.70, -2.75) | <.0001 |
-3.20 (-4.08, -2.31) | -0.53 (-1.23, 0.17) | 2.67 (1.40, 3.93) | 0.0001 |
| BFP (%) | 38.12 (36.50, 39.73) | 36.42 (34.71, 38.12) | -1.70 (-2.45, -0.95) | <.0001 |
36.53 (35.00, 38.05) | -1.59 (-2.36, -0.82) | 0.0002 |
-1.70 (-2.45, -0.95) | 0.11 (-0.74, 0.97) | 1.81 (0.40, 3.22) | 0.0132 |
| BFM (kg) | 29.32 (27.22, 31.42) | 27.21 (25.06, 29.36) | -2.11 (-2.86, -1.36) | <.0001 |
27.23 (25.09, 29.36) | -2.10 (-2.88, -1.31) | <.0001 |
-2.11 (-2.86, -1.36) | 0.02 (-0.67, 0.70) | 2.13 (0.93, 3.33) | 0.0009 |
| MSC (kg) | 33.11 (29.24, 36.98) | 32.66 (29.01, 36.32) | -0.45 (-0.93, 0.04) | 0.0700 | 32.45 (28.73, 36.18) | -0.66 (-1.11, -0.20) | 0.0054 |
-0.47 (-0.93, 0.04) | -0.21 (-0.63, 0.22) | 0.24 (-0.56, 1.03) | 0.5489 |
| NRS | 7.77 (7.23, 8.31) | 3.95 (3.30, 4.60) | -3.81 (-4.57, -3.05) | <.0001 |
3.93 (3.15, 4.71) | -3.84 (-4.67, -3.01) | <.0001 |
Data were expressed as mean (95% confidence interval).
BMI: body mass index, WC: waist circumstance, HC: hip circumstance, BFP: body fat percent, BFM: body fat mass, MSC: muscle mass, NRS: numeric rating scale.
P-value by paired t-test, *P-value<0.05.
