Fig. 4. Effects of AFB extract on the histological changes of liver and adipose tissues in HFD-induced obesity mice. The liver (A), pancreas (C), epididymis fat (D), and brown fat (E) tissues were stained with hematoxylin and eosin and then were observed under microscope (x100). (B) The weights of liver were measured in mice at 12 week. Data were presented as mean±standard deviation (n=5 per a group). **P<0.01, and ***P<0.001 vs. Nor (a) or HFD group (b). Nor: normal group, HFD: high fat diet-induced obesity control group, AFB: Allii Fistulosi Bulbus extract (500 mg/kg)-administrated group, Met: metformin (500 mg/kg)-administrated group. Arrows were shown pathological changes of each tissue.