Fig. 5. Effects of C-DM4 extract on the histological changes of epididymal fat tissues in high fat diet-induced obesity mice. The fat tissues were stained with hematoxylin and eosin and observed under microscope (x200). The weights of fat were measured in mice at 12 week. Cont: normal group, HFD: high fat diet-induced diabetic control group, C-DM4: C-DM4 at 500 mg/kg-administrated group, Met: metformin-administrated group.